Warhammer 40.000 Roleplay è una serie di giochi di ruolo con un sistema di regole comune, che condividono la stessa ambientazione gotica e tecno-fantasy del gioco di miniature Warhammer 40.000. Nel primo gioco, Dark Heresy, i giocatori interpretano un gruppo legato all'Inquisizione. Rogue Trader tratta i viaggi stellari, il commercio, l'esplorazione e gli Xeno. Deathwatch permette di interpretare i potenti Space Marines. Black Crusade vede protagonisti e cultisti del Caos, mentre Only War offre la possibilità di giocare con i temerari soldati della Guardia Imperiale. La Black Industries ha deciso di ambientare il gioco in un settore di spazio nuovo e mai descritto precedentemente, il settore Calixis, all'interno del Segmentum Obscurus. 

Questo settore è adiacente allo Scarus, ambientazione della trilogia di Eisenhorn di Dan Abnett. Inizialmente sviluppato dalla Black Industries e dalla Green Ronin, i diritti del gioco sono passati alla Fantasy Flight nel 2008, che ha continuato la pubblicazione di manuali e supplementi.

Estratto sull'Ambientazione

Da più di cento secoli l’Imperatore giace immobile sul Trono d’Oro della Terra. Egli, il Signore dell’Umanità per volere divino, controlla milioni di mondi grazie alla potenza dei suoi infaticabili eserciti. E’ una carcassa in decomposizione tenuta in vita dalle scienze ormai dimenticate dell’Oscura Era della Tecnologia. A Lui, Signore incontrastato dell’Imperium, sono sacrificate ogni giorno mille anime di modo che non muoia mai.
Durante la sua eterna esistenza, l’Imperatore è costantemente vigile. Guidate dal suo Volere, indomite flotte di astronavi da guerra attraversano i miasmi del Warp infestato da Demoni, l’unica strada fra stelle lontane, guidate solo dal faro dell’Astronomican, manifestazione del potere dell’Imperatore. Vaste armate combattono nel Suo nome su innumerevoli pianeti, eppure sono appena sufficienti per tener testa alle onnipresenti minacce di Alieni, Eretici, Mutanti e ancor più tetre presenze.
Essere un uomo in questo periodo significa essere uno su miliardi di miliardi di esseri umani. Significa vivere in un regime violento e innaturale come mai ve ne è stato prima. Ma tu non sei un semplice individuo...

Di seguito i manuali ufficiali pubblicati.

Dark Heresy - Manuali Pubblicati in Italiano

01. Dark Heresy - Manuale Base
02. Kit dell'Arbitro di Gioco
03. Brucia l'Eretico
04. Il Manuale dell'Inquisitore
05. La Soglia dell'Oscurità (avventura gratuita)

Rogue Trader - Manuali Pubblicati in Italiano

01. Rogue Trader - Manuale Base
02. Kit dell'Arbitro di Gioco
03. Il Richiamo del Firmamento
04. Nella Tempesta
05. Il Tesoro Abbandonato (avventura gratuita)

Dark Heresy

Dark Heresy - Core Rulebook, including a pre-written adventure (ISBN 978-1844164356)
The Game Master's Kit - A game master's screen for Dark Heresy and a 32-page booklet that includes a pre-written adventure, xenos generator, and new rules for poisons and toxins
Character Folio - A notebook designed to be a combined character sheet and journal
Inquisitor's Handbook - Supplement, introduces the Adepta Sororitas career path and new home world types as well as an expanded rule system for the original home worlds, expanded armoury, and expanded skill rules
Purge the Unclean - An adventure anthology containing three adventures, each focusing on a different genre or play style
Shattered Hope - A free preview adventure available for download on the Black Industries web site
Edge of Darkness - A free preview adventure by Alan Bligh (and others) available for download on the Fantasy Flight Games web site
Disciples of the Dark Gods - Supplement, information detailing cults and other various threats within the game setting. Includes a Full Length Adventure.
Creatures Anathema - Supplement, a "Bestiary of Aliens, Beasts, and Daemons" for use as enemies
The Radical's Handbook - Supplement, introduces means of playing Radical (Heretical) character types as well as new gear and advances.
Ascension - Supplement, introduces advanced career paths enabling players to become Inquisitors or Throne Agents, high-powered acolytes who bridge the power gap between Dark Heresy and Rogue Trader characters.
Tattered Fates: The Haarlock Legacy Volume 1 - Part 1 of a 3 part adventure campaign
Damned Cities: The Haarlock Legacy Volume 2 - Part 2 of a 3 part adventure campaign
Dead Stars: The Haarlock Legacy Volume 3 - Part 3 of a 3 part adventure campaign
Blood of Martyrs - Supplement, includes new rules, backgrounds, alternate careers and equipment for playing servants of the Adeptus Ministorum, the church of the Imperium The Black Sepulchre: The Apostasy Gambit Volume 1 - Part 1 of a 3 part adventure campaign
The Church of the Damned: The Apostasy Gambit Volume 2 - Part 2 of a 3 part adventure campaign
The Chaos Commandment: The Apostasy Gambit Volume 3 - Part 3 of a 3 part adventure campaign
Daemon Hunter - Supplement, expanding on the inquisitors of Ordo Malleus and the Grey Knight chapter of Space Marines.
Book of Judgement - Supplement, expanding on the Adeptus Arbites and Scum of the Calix Sector with new rules, backgrounds, alternate careers and equipment for playing servants or recidivists of the Adeptus Arbites, the federal law of the Imperium
The Lathe Worlds - Supplement, revealing the secret history of the Lathe Worlds, from the founding to the current struggles against tech-heresy. In the book there are alternate careers and equipment for players.

Rogue Trader

Rogue Trader - Core Rulebook, including a pre-written adventure (ISBN 978-1589946750)
The Game Master's Kit - A game master's screen for Rogue Trader and a booklet that includes a pre-written adventure, an NPC starship generator and a star system generator
Lure of the Expanse - A sourcebook containing three adventures Forsaken Bounty - A free preview adventure available for download on the Fantasy Flight Games web site
Dark Frontier - A free preview adventure available for download on the Fantasy Flight Games web site
Into the Storm - A sourcebook containing rules about creating alien ("xenos") player characters (Kroot and Ork species), vehicles and gear
Edge of the Abyss - A sourcebook containing descriptions of the worlds of the Koronus expanse, Rogue Trader's main setting
The Frozen Reaches - Part 1 of the 3 part The Warpstorm Trilogy campaign
Citadel of Skulls - Part 2 of the 3 part The Warpstorm Trilogy campaign
Fallen Suns - Part 3 of the 3 part The Warpstorm Trilogy campaign
Battlefleet Koronus - A sourcebook covering starships, including the history of the Imperial Navy
Hostile Acquisitions - A supplement, expanding on career paths with a distinctly "scoundrel" feel to them, as well as additional rules on making enemies with a Nemesis Origin path. Provides stats and rules to play on the other side of Imperial Law
The Koronus Bestiary - A supplement for Rogue Trader, is a detailed compendium of deadly beasts, hostile xenos, unholy daemons, and other dangers that fill the uncharted regions of the Koronus Expanse
The Soul Reaver - A sourcebook on Dark Eldar in the Koronus Expanse, including an adventure campaign about a Dark Eldar city in the Webway and rules for creating Dark Eldar player characters The Navis Primer - A sourcebook covering warp related aspects of the game with an emphasis on astropaths and navigators, as well as alternate career ranks
Stars of Inequity - A supplement focusing on the worlds of the Koronus Expanse Faith and Coin - A supplement that focuses on cooperation of Explorers and Ecclesiarchy

Deathwatch

Deathwatch - Core Rulebook, including a pre-written adventure (ISBN 978-1589947788)
The Game Master's Kit - A game master's screen for Deathwatch and a booklet that includes a pre-written adventure, and additional NPCs and antagonists
The Emperor Protects - An adventure anthology containing three adventures
Rites of Battle - A sourcebook including new character options, advanced specialties such as Chaplain, Chapter creation rules, weapons, armour and vehicle rules
Mark of the Xenos - A sourcebook of aliens, heretics, and daemons for use as foes
The Achilus Assault - A sourcebook covering the details of the Jericho Reach campaign area, the default setting for the Deathwatch RPG. The book provides extensive information for any Warhammer 40,000 RPG type campaign, leaning toward covering Deathwatch aspects.
First Founding - A sourcebook that adds the four remaining First Founding chapters not included in previous Deathwatch books. This book also includes new specialties, solo rules and allows Deathwatch Space Marines to have followers.
The Jericho Reach - A supplement that provides information on the Jericho Reach, includes a full adventure
Rising Tempest - An adventure in three parts for Deathwatch
Honour the Chapter - A supplement that provides information and character creation options for Chapters from the Second and subsequent Foundings
The Outer Reach - A supplement detailing the Dead Cabal and Necrons of the Suhbekhar dynasty
Ark of Lost Souls - A supplement that provides rules for Space Hulks, includes an adventure set on board an infamous
Space Hulk Emperor's Chosen - A supplement that focuses on Deathwatch veterans.

Black Crusade

Black Crusade - Core Rulebook, including a pre-written adventure (ISBN 978-1616611439)
The Game Master's Kit - A game master's screen for Black Crusade and a booklet that includes a pre-written adventure, additional NPCs, and expanded rules
Hand of Corruption - An adventure in three acts for Black Crusade
The Tome of Fate - A supplement that focuses on Tzeentch, the Chaos God of Change. The first of four books focusing on the Ruinous Powers
The Tome of Blood - A supplement that focuses on Khorne, the Lord of Skulls. The second of four books focusing on the Ruinous Powers
The Tome of Excess - A supplement that focuses of Slaanesh, the Prince of Pleasure. The third of four books focusing on the Ruinous Powers.
The Tome of Decay - A supplement that focuses of Grandfather Nurgle, the Master of Plagues. The last of four books focusing on the Ruinous Powers

Only War

Only War - Core Rulebook, including a pre-written adventure (ISBN 978-1616614690)
The Game Master's Kit - A game master's screen for Only War and a booklet that includes a pre-written adventure and additional NPCs
Final Testament - An adventure in three parts for Only War
No Surrender - An adventure in three parts for Only War
Hammer of the Emperor - A supplement that focuses on the Spinward Front's conflicts and its participants
Enemies of the Imperium - A supplement that gives deeper insight into the deadly foes of the Imperial Guard who lurk in the Spinward Front
Shield of Humanity - A supplement that focuses on support specialists.